Nanotechnology Applications in Cancer Drug Delivery Systems: A Review
J. Environ. Nanotechnol., Volume 14, No 2 (June 2025) pp. 458-470
Abstract
Nanotechnology of medicine, particularly therapy, by novel longstanding in drug delivery. Cancer, a complex and multifaceted disease, demands innovative therapeutic approaches capable of addressing its heterogeneity, drug resistance, and adverse effects associated with conventional avenues for nanomaterials, dimensions, large-to-volume ratio, and the ability to be functionalized for specific purposes. Moreover, advancements in nanotechnology have enabled chemotherapeutics, siRNA, to address the multifactorial nature of cancer and overcome drug resistance mechanisms. Advancements, nanotechnology significant challenges. Issues such as scalability in manufacturing, reproducibility, and biocompatibility, hinder cancer and further complicate the design of universally effective nanocarriers, necessitating tailored approaches for different cancer types and patient populations. This review examines the developments driven by cancer highlighting design principles and their impact on improving therapeutic outcomes. It also offers insights into emerging trends and future directions. With continuous innovation and interdisciplinary collaboration, nanotechnology holds immense potential to transform cancer therapy, and targeted, patient-specific treatment modalities.
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Reference
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