Synthesis and Characterization of Schiff Base Cu Salpn Complexes and Biological Potential Study
J. Environ. Nanotechnol., Volume 8, No 1 (2019) pp. 34-37
Abstract
Schiff bases are versatile ligands synthesized from the condensation of an amino compound with carbonyl compounds. In this work, the biological activity of the transition metal complexes derived from the Schiff base ligands has been widely studied. Salpn is the common name for a chelating ligand, properly termed as N, N'-bis (salicylaldehyde) -1, 2-propane diamine. The complexes of copper with Schiff bases have wide applications in food industry, dye industry, analytical chemistry, catalysis, fungicidal, agrochemical, anti-inflammable, anti-radical and biological activities. A new Cu-salpn complex has been synthesized from the reaction of salpn with copper sulphate pentahydrate (CuSO4.5H2O). The synthesized complex was characterized by IR and UV spectral techniques. Antimicrobial activity has been tested against the bacteria, viz, Antinomyces israelii, Corynebacterium diphtheria and Staphylococcus aureus by using Agar well diffusion method.
Full Text
Reference
Nair, R., Shah, A., Baluja, S. and Chanda, S., Synthesis and antibacterial activity of some schiff base complexes, J. Serb. Chem. Soc., 71(7), 733–744(2006).
https://doi.org/10.2298/JSC0607733N
Navan R., Bhalodia, Shukla, V. J., Antibacterial and antifungal activities from leaf extracts of Cassia fistula : An ethnomedicinal plant, J. Adv. Pharm. Technol. Res., 2(2), 104-109(2011).
https://doi.org/10.4103/2231-4040.82956
Parastoo Karimi Alavijeh, Parisa Karimi Alavijeh and Devindra Sharma, A study of antimicrobial activity of few medicinal herbs, Asian J. Plant and Research, 2(4), 496-502(2002).
Reddy, P. S., Jamil, K., Madhusudhan, P., Anjani, G. and Das, B., Antibacterial activity of isolates from Piper longum and Taxus baccata, Pharmaceutical Biol., 39(3), 236–238(2001).
https://doi.org/10.1076/phbi.39.3.236.5926
Rishu Katwal, Harpreet Kaura and Brig Kishore Kapur, Application of Copper- Schiff’s Base Complexes : A Review, Sci. Revs. Chem. Commun., 3(1), 01-15(2013).
Salehia, M., Kubickib, M., Dutkiewiczb, G., Rezaeic, A., Behzada, M. and Etminania, S., Synthesis, Characterization, Electrochemical Studies and Antibacterial Activities of Cobalt (III) complexes with SalpnTipe schiff base ligands. Crystal Structure of trans [CoIII(L1)(Py)2]ClO4, Russian Journal of Coordination Chemistry, 39(10), 716–722(2013).
https://doi.org/10.1134/S1070328413100084
Shahidi, B. H., Evaluation of antimicrobial properties of Iranian medicinal plants against Micrococcus luteus, Serratia marcescens, Klebsiella pneumonia and Bordetella bronchoseptica, Asian J. Plant Sci., 3, 82–86(2004).
