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Journal of Environmental Nanotechnology

(A Quarterly Peer-reviewed and Refereed International Journal)
ISSN(Print):2279-07 48; ISSN(Online):2319-5541
CODEN:JENOE2

Synthesis of 2-Methyl -3,4,5,10-Tetrahydro-Pyrrolo [3,2-A] Carbazole-Ethyl Carboxylate Derivatives and Evaluation of their Binding Affinity with CT-DNA

Abstract

A new class of heterocyclic compound, substituted 2-methyl-3,4,5,10-tetarahydro-pyrrolo[3,2- a]carbazole-1-ethyl carboxylate derivatives have been prepared from 1-oxo-1,2,3,4,-tetrahydrocarbazoles. The structural features were determined by analytical and spectral techniques. DNA binding study of the compounds was investigated by absorption titration experiments which indicated that the compounds showed good binding affinity to CT-DNA via intercalation.

Article Type: Research Article

Corresponding Author: M. Sekar 3  

Email: mmsekar7@gmail.com

This article has not yet been cited.

M. Saravanabhavan 1,  V. Murugesan 2,  M. Sekar 3*.  

1, 2, 3. Department of Chemistry, Sri Ramakrishna Mission Vidyalaya College of Arts and Science, Coimbatore, TN, India.

J. Environ. Nanotechnol. Volume 2, No.4 pp.62-67
ISSN: 2279-0748 eISSN: 2319-5541
ENT132056.pdf
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