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Journal of Environmental Nanotechnology

(A Quarterly Peer-reviewed and Refereed International Journal)
ISSN(Print):2279-07 48; ISSN(Online):2319-5541

Antibacterial and Antifungal Activity of Opuntia Dillenii (Cactaceae) Fruit Extract


The antimicrobial activity of plant extracts and phytochemicals was evaluated with antibiotic susceptible and resistant micro organisms. Methanolic extract of Opuntia dillenii (OD) was tested for its antibacterial (plate hole method) activity against fourteen different bacterial strains. From the results, it is deduced 100 % of methanolic extract were active in concentration of 1000 μg/ml, 93 % active in concentration of 500 μg/ml, 87.5 % active in concentration of 250 μg/ml, 50 % active in concentration of 125 μg/ml and no activity in lowest test concentration of 62.5μg/ml. Antifungal activity against six different fungal organisms were studied and the results were indicated that the 1000 μg/ml & 500 μg/ ml showed good activity in all fungus (100%). The methanolic extracts in concentration of 250 μg/ml (83%) and 125 μg/ ml (33 %) showed moderate activity in all tested microorganisms. Oxy tetracycline and Amphotericin B with concentration of 1000 μg/ml were used as a standard drug for antibacterial and antifungal studies respectively.

Article Type: Orginal research Article

Corresponding Author: A.P. Saravana Kumaar  1  

Email: saravncp@gmail.com

This article has not yet been cited.

A.P. Saravana Kumaar  1*,  J. Vanitha  2,   K. Venkateshwaran 3,  K. Srikanth Reddy  4,  D. Karthikeyan  5.  

1. Department of Pharmaceutical Biotechnology, JJ College of Pharmacy, Mahashwaram, Hyderabad, AP, India

2. Department of Pharmaceutical Analysis, The Erode College of Pharmacy, Tamilnadu, India.

3. Department of Pharmaceutical Technology, Anna University of Technology, Tiruchirapalli, Tamilnadu, India.

4. Department of Pharmaceutical Biotechnology, J J College of Pharmacy, Maheswaram, Andhra Pradesh, India

5. Department of Pharmaceutics, Shri Krupa Institute of Pharmaceutical Sciences, Siddipet, Velkatta, Medak, Andhra Pradesh, India.

J.Environ. Nanotechnol., Volume 2, No. 1 (2013) pp.16-19
ISSN: 2279-0748 eISSN: 2319-5541
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Ergene, A., Guler, P., Tan, S., Mirci, S., Hamzaoglu, E., Duran, A., Antibacterial and antifungal activity of Heracleum sphondylium subsp. Artvinens, Afr J Biotech., 5 (11), 1087-1089 (2006).

Gupta, RS., Sharma, R., Sharma, A., Antispermatogenic effect and chemical investigation of Opuntia dillenii. Pharm Biol., 40, 411-415 (2002).http://dx.doi.org/10.1076/phbi.40.6.411.8437

Nascimento, G.G.F., Locatelli, J., Freitas, P.C., Silva, G.L., Antibacterial activity of plant extracts and phytochemicals on antibiotic resistant bacteria, Braz J Microbiol., 31, 247-256 (2000).http://dx.doi.org/10.1590/S1517-83822000000400003

Rubeena Saleem., Mohammad Ahmad., Aisha Azmat., Hypotensive activity, toxicology and histopathology of opuntioside-I and methanolic extract of Opuntia dillenii. Biol Pharm Bull., 28, 844 – 851 (2005).

Saravana Kumar, A., Avijit Mazumder., Saravanan V.S., Antihyperlipidemic activity of Camellia sinensis leaves in Triton-WR 1339 induced albino rats, Phcog Mag., 4, 60 - 64 (2008).

Sharavanakumar, A.P., Vanitha, J., Venkateswaran, K., Srikanth Reddy, Simon, K.T., Jopsy, Karthikeyan, D., Antibacterial activity of methanolic extract of Thespesia populnea (Malvaceae) Flower, J. Environ. Nanotechnol., 1(1), 50-52 (2012).http://dx.doi.org/10.13074/jent.2012.10.121018

Sathiya, M., Parimala, P., Muthuchelian, K., Preliminary phytochemical screening and antimicrobial studies on the ethanolic leaf extracts of Nyctanthes arvortristis linn. Ethnobot Letters., 12,337 -342 (2008).

Yingkun Qiu., Yingjie Chen., Yupin Pei., Constituents with radical scavenging effect of Opuntia dillenii ; Structure of New pyrones and Flavonol Glycosides. Chem Pharm Bull., 50, 1507-1510 (2002).http://dx.doi.org/10.1248/cpb.50.1507